Renal aquaporin-3 expression in rats with obstructive jaundice
نویسندگان
چکیده
منابع مشابه
Renal failure in obstructive jaundice--clinical aspects.
The patient with obstructive jaundice has an increased risk ofdeveloping renal failure. The commonest clinical situations in which this is seen is after surgical operation, as a result of percutaneous cholangiography or in association with severe ascending cholangitis. The risk of acute renal failure is decreased by ensuring adequate hydration and maintaining a high urine flow, if necessary usi...
متن کاملRenal failure in obstructive jaundice--pathogenic factors.
In the patient with obstructive jaundice, preliminary dehydration, combined with the toxic effects of free bilirubin and serum bile acids, together with factors which cause inhibition of fibrinolysis, determine a high degree of renal susceptibility to ischaemia. Evidence from animals and man suggests that intravascular coagulation determined by endotoxaemia from the obstructed biliary system oc...
متن کاملThe Renal Excretion of Bilirubin in Dogs with Obstructive Jaundice.
Dogs and humans excrete only conjugated bilirubin in the urine, principally the diglucuronide, and unconjugated bilirubin is not excreted by the kidneys (1). Previous studies concerning the renal excretion of bilirubin have not resolved the issue of whether it is filtered through the glomeruli or is secreted by the tubules (2, 3). Bilirubin in the plasma has been reported to be completely bound...
متن کاملThe Role of Endotoxaemia in the development of Renal Disorders Experimental Obstructive Jaundice in Rats
In rats with 2-week obstructive jaundice the sensitivity to endotoxin was studied and the effect of a single dose of endotoxin on histological development in the kidney, liver and spleen was also investigated. We were tested the effect on accumulation and distribution within organs, of fibrinogen labelled with radioactive iodine I 125. We showed an increased sensitivity to endotoxin in obstruct...
متن کاملRenal function in chronic obstructive jaundice: a micropuncture study in rats.
1. We have studied kidney structure and func tion in female Sprague-Dawley rats with chronic obstructive jaundice after bile-duct ligation and section and in age-matched sham-operated control animals. 2. High bile-duct ligation and section resulted in immediate hyperbilirubinaemia and progressive hepatomegaly with histological evidence of bileduct proliferation and periportal inflammation and ...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2008
ISSN: 2219-2859
DOI: 10.11569/wcjd.v16.i1.10